標題圖片
醫師介紹圖片

醫師介紹

科別:
周邊神經科
職稱:
主治醫師
姓名:
廖翊筑 Yi-Chu Liao
現任:
台北榮總 周邊神經科 主治醫師
國立陽明大學 神經學科 兼任教授
學經歷 :
學歷:
私立高雄醫學大學,醫學研究所博士
私立高雄醫學大學,醫學遺傳所碩士
國立陽明大學醫學院,醫學士

經歷:
2014/4-至今 臺北榮民總醫院神經醫學中心,周邊神經科主治醫師
2008/07-2014/03 臺中榮民總醫院,神經內科主治醫師
2004/5-2006/05 財團法人義大醫院,神經內科主治醫師
1999/09-2004/4 臺北榮民總醫院,神經內科住院醫師
台灣神經學學會第十九屆理事
台灣頭痛學會第二屆至第五屆理事

臨床專長: 遺傳性腦部小血管疾病, 多發性硬化症, 視神經脊髓炎, 週邊神經病變, 肌無力症

學術專長: 易感性基因研究
研究方向: 遺傳性腦部小血管疾病, 遺傳性腦白質病變, 多發性硬化症, 視神經脊髓炎

得獎紀錄:
2014 科技部 吳大猷先生紀念獎
2014 李鎮源教授 研究青年學者獎
2019 科技部 優秀年輕學者研究計畫
2018 台北榮總 醫師學術論文獎 第一名
2019 台北榮總 醫師學術論文獎 佳作
學術研究 :

媒體影音報導:
多發性硬化症病灶多元 及早介入診治有助預後 (健康醫療網新聞 2018年5月23日)
https://www.healthnews.com.tw/news/article/38103 

 

論文發表:

 

  1. Yi-Chung Lee, Chih-Ping Chung, Ming-Hong Chang, Shuu-Jiun Wang, Yi-Chu Liao (通訊作者). NOTCH3 cysteine-altering variant is an important risk factor for stroke in the Taiwanese population. Neurology 2020;94:e87-e96.
  2. Chih-Ping Chung, Jiun-Wei Chen, Feng-Chi Chang, Wei-Chi Li, Yi-Chung Lee, Li-Fen Chen*, Yi-Chu Liao* (共同通訊作者). Cerebral Microbleed Burdens in Specific Brain Regions Are Associated With Disease Severity of Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy. J Am Heart Assoc 2020 Jul 7;9(13):e016233
  3. Hsu YH, Lin KP, Guo YC, Tsai YS, Liao YC* (共同通訊作者), Lee YC*. Mutation spectrum of Charcot-Marie-Tooth disease among the Han Chinese in Taiwan. Ann Clin Transl Neurol. 2019;6(6):1090-1101.
  4. Lin YC, Lee YC, Hsu TY, Liao YC* (共同通訊作者), Soong BW*. Comparable progression of spinocerebellar ataxias between Caucasians and Chinese. Parkinsonism Relat Disord. 2019 May;62:156-162.
  5. Liao YC(第一作者), Lee YC. Reply: A Novel WARS Mutation Causes Distal Hereditary Motor Neuropathy in a Chinese Family. Brain. 2019 Sep 1;142(9):e50.
  6. Lee YC, Chung CP, Chao NC, Fuh JL, Chang FC, Soong BW, Liao YC (通訊作者). Characterization of Heterozygous HTRA1 Mutations in Taiwanese Patients With Cerebral Small Vessel Disease. Stroke. 2018;49(7):1593-1601.
  7. Liao YC (第一與通訊作者), Tsai PC, Lin TS, Hsiao CT, Chao NC, Lin KP, Lee YC. Clinical and Molecular Characterization of PMP22 point mutations in Taiwanese patients with Inherited Neuropathy. Sci Rep. 2017 Nov 10;7(1):15363
  8. Tsai PC, Soong BW, Mademan I, Huang YH, Liu CR, Hsiao CT, Wu HT, Liu TT, Liu YT, Tseng YT, Lin KP, Yang UC, Chung KW, Choi BO, Nicholson GA, Kennerson ML, Chan CC, De Jonghe P, Cheng TH, Liao YC* (共同通訊作者), Züchner S, Baets J, Lee YC*. A recurrent WARS mutation is a novel cause of autosomal dominant distal hereditary motor neuropathy. Brain 2017;140(5):1252-1266
  9. Chen YH, Lee YC, Tsai YS, Guo YC, Hsiao CT, Tsai PC, Huang JA, Liao YC*(共同通訊作者), Soong BW*. Unmasking adrenoleukodystrophy in a cohort of cerebellar ataxia. PLoS One.2017; 12(5):e0177296.
  10. Hsu PY, Hsi E, Wang TM, Lin RT,Liao YC*(共同通訊作者), Juo SH*. MicroRNA let-7g Possesses a Therapeutic Potential for Peripheral Artery Disease. J Cell Mol Med. 2017 Mar;21(3):519-529.
  11. Tsai PC, Tsai YS, Soong BW, Huang YH, Wu HT, Chen YH, Lin KP, Liao YC*(共同通訊作者), Lee YC* A novel DNAJB6 mutation causes dominantly inherited distal‐onset myopathy and compromises DNAJB6 function Clin Genet. 2017;92(2):150-157.
  12. Liao YC (第一作者), Hsiao CT, Fuh JL, Chern CM, Lee WJ, Guo YC, Wang SJ, Lee IH, Liu YT, Wang YF, Chang FC, Chang MH, Soong BW. Characterization of CADASIL among the Han Chinese in Taiwan: Distinct Genotypic and Phenotypic Profiles. PLoS One.2016; 10(8):e0136501.
  13. Lee YC, Tsai PC, Guo YC, Hsiao CT, Liu GT, Liao YC*(共同通訊作者), Soong BW* Spinocerebellar ataxia type 36 in the Han Chinese. Neurol genet 2016;2(3):e68.
  14. Liao YC (第一作者), Liu YT, Tsai PC, Chang CC, Huang YH, Soong BW, Lee YC. Two Novel De Novo GARS Mutations Cause Early-Onset Axonal Charcot-Marie-Tooth PLoS One. 2015; 10(8):e0133423.
  15. Guo YJ, Chang MH, Chen PL, Lee YS, Chang YC, Liao YC* (通訊作者). Predictive Value of Plasma d-Dimer Levels for Cancer-Related Stroke: A 3-Year Retrospective Study. J Stroke Cerebrovasc Dis., 2014 Apr;23(4):e249-54
  16. Liao YC(第一作者), Wang YS, Hsi E, Chang MH, You YZ, Juo SH*. MicroRNA-765 influences arterial stiffness through modulating apelin expression. Mol Cell Endocrinol 2015 Aug 15;411:11-9
  17. Liao YC(第一作者), Liu PY, Lin HF, Lin WY, Liao JK, Juo SH*.Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression. J Mol Cell Cardiol. 2015 Feb;79:180-6.
  18. Liao YC(第一作者), Lee WJ, Hwang JP, Wang YF, Tsai CF, Wang PN, Wang SJ, Fuh JL*. ABCA7 gene and the risk of Alzheimers disease in Han Chinese in Taiwan. Neurobiol Aging.2014 Oct;35(10):2423.e7-2423.e13.
  19. Liao YC(第一作者), Wang YS, Guo YC, Lin WL, Chang MH, Hank Juo SH*. Let-7g improves multiple endothelial functions through targeting TGF-β and SIRT-1 signaling. J Am Coll Cardiol, 2014 Apr 29;63(16):1685-94.
  20. Liao YC(第一作者), Lin HF, Guo YC, Chen CH, Huang ZZ, Juo SH, Lin RT. Lack of association between a functional variant of the BRCA-1 related associated protein (BRAP) gene and ischemic stroke. BMC Med Genet., 2013 Jan 28;14:17.
  21. Juo SH, Liao YC* (共同第一作者), Lin HF, Chen PL, Lin WY, Lin RT. Lack of association between a functional genetic variant of connexin 37 and ischemic stroke in a Taiwanese population. Thrombosis research, 129(4):465-e69
  22. Lee YC, Liao YC* (共同第一作者), Wang PS, Lee IH, Lin KP, Soong BW*. Comparison of cerebellar ataxias: A three-year prospective longitudinal assessment. Mov Disord, 2011;26(11):2081-7.
  23. Liao YC (第一作者), Chou WW, Li YN, Chuang SC, Lin WY, Lakkakula BV, Yu ML, Juo SH*Apelin gene polymorphism influences apelin expression and obesity phenotypes in Chinese women . Am J Clin Nutr, 2011;94:921–8
  24. Liao YC(第一作者), Wang YS, Guo YC, Ozaki K, Tanaka T, Lin HF, Chang MH, Chen KC, Yu ML, Sheu SH, Juo SH*. BRAP activates the inflammatory cascades and increases the risk for carotid atherosclerosis. Mol Med. 2011;17(9-10):1065-74
  25. Liao YC(第一作者) Lin HF, Guo YC, Yu ML, Liu CK, Juo SH. Sex-differential Genetic Effect of Phosphodiesterase 4D (PDE4D) on Carotid Atherosclerosis. BMC Med Genet. 2010 Jun 12;11:93.
  26. Liao YC(第一作者), Lin HF, Rundek T, Cheng R, Guo YC, Sacco RL, Juo SH. Segment-specific Genetic Effects on Carotid Intima-Media Thickness: The Northern Manhattan Study. Stroke 2008 Dec;39(12):3159-65.
  27. Liao YC(第一作者), Lin HF, Rundek T, Cheng R, Hsi E, Sacco RL, Juo SH. Multiple Genetic Determinants of Plasma Lipid Levels in Caribbean Hispanics. Clin Biochem. 2008 Mar;41(4-5):306-12.
  28. Liao YC(第一作者), Liu RS, Teng EL, Lee YC, Wang PN, Lin KN, Chung CP, Liu HC. Cognitive Reserve: A SPECT Study of 132 Alzheimers Disease Patients With an Education Range of 0-19 Years. Dement Geriatr Cogn Disord. 2005;20(1):8-14.
  29. Liao YC(第一作者), Fuh JL, Lirng JF, Lu SR, Wu ZA, Wang SJ. Bathing Headache: A Variant of Idiopathic Thunderclap Headache. Cephalalgia. 2003 Nov;23(9):854-9.
  30. Liao YC(第一作者), Liu RS, Lee YC, Sun CM, Liu CY, Wang PS, Wang PN, Liu HC. Selective Hypoperfusion of Anterior Cingulate Gyrus in Depressed AD Patients: A Brain SPECT Finding by Statistical Parametric Mapping. Dement Geriatr Cogn Disord. 2003;16(4):238-44 

Last updated 2020.9.29